Macular edema of the retina is usually secondary to various retinal diseases, such as venous obstruction or diabetic fundopathy. For the treatment of this condition, it is usually necessary to deal with the specific cause in the early stage, for example, oral medications to activate blood circulation or control blood sugar can be chosen to reduce the development of the lesion. For the reduction of macular edema, intraocular injection of tretinoin or ranibizumab injection can be given. When more obvious complications occur, such as macular edema leading to retinal detachment or macular fissure formation, early vitrectomy should be performed in such cases. Therefore, if macular edema exists in the eye, it is important to go to the hospital early to improve the fundus examination, and then treat the symptoms, and during the treatment period, it is also necessary to regularly review and adjust the treatment plan according to the changes of the disease.