The main reason for the recurrence of condyloma acuminata is generally considered to be: 1, latent infection: the local mucous membrane appearance is normal and the white acetate test is negative, but the presence of HPV can be detected through molecular biology methods, it is believed that HPV latent infection is one of the main reasons for the recurrence of CA. 2, subclinical infection: lesions that cannot be identified by the naked eye, but positive white acetate test, can be manifested as: tiny non-tipped warts, tiny papillary elevation, normal appearance of the ring lesions. The subclinical infected lesions can be applied topically with 3% to 5% acetic acid solution or wet compress for 5 to 10 minutes, which can be whitened in the infected area, the so-called “white acetate phenomenon”. The presence of subclinical infection is also related to the recurrence of the disease. 3, special parts of the human papillomavirus (HPV) exists: such as the female cervix, male urethral orifice HPV infection, because the location of the infection is deep, not easily detected, treatment is often incomplete, and the local environment is conducive to the growth of warts. 4, the patient’s personal hygiene habits: male circumcision, female vulvovaginal infections and the increase in secretions caused by the local moist environment, etc., conducive to HPV growth, resulting in recurrence. 5, recurrence is often related to the body’s immunity: the body’s immunity is low, such as malignant tumors, organ transplants, long-term application of immunosuppressants, etc., the chances of recurrence increased. 6.Sexual partners: The recurrence rate is very low if the sexual partner is examined and treated at the same time and safety measures are done, on the contrary, the recurrence rate is higher if the sexual partner is concealed and no safety measures are taken. 7, combined with other sexually transmitted diseases: such as genital herpes, mucosal barrier damage, so that the ability to resist HPV infection is reduced, the chance of recurrence increased.