In recent years, more and more people, especially those in coastal areas, are suffering from thyroid nodules, most of which are found during medical checkups. So what should I do if I have a thyroid nodule? First of all, coastal areas have a high prevalence of thyroid nodules, and there is a clear correlation between excessive iodine intake and the development of thyroid nodules. When a thyroid nodule is found, there is no need to worry too much because most thyroid nodules are benign. In ultrasonography, the terms used to describe thyroid nodules include: size, shape, border, blood flow, calcification points, lymph nodes, etc. Just one abnormal indicator cannot determine the benignity or malignancy of a thyroid nodule. The initial determination of benign and malignant thyroid nodules is based on a comprehensive assessment. Secondly, in clinical work, the gold standard for thyroid nodule diagnosis is that tumor cells are seen on fine needle aspiration cytology of the thyroid gland. However, due to the small size of the tumor or other factors, the specificity of fine needle aspiration is high, but the sensitivity is not high; if the aspiration can be performed under ultrasound localization, the sensitivity will be greatly increased. Finally, if thyroid nodules are determined to be malignant, surgical treatment is preferred, except for patients with advanced metastases, which have a high survival rate of 5-10 years after thyroid nodule surgery and basically do not affect life expectancy.