1, physical cooling and antipyretics used in combination, the temperature drops faster than the use of antipyretics alone. 2, the dose of antipyretics should not be too large to prevent excessive sweating of the child resulting in deficiency, encourage more water . 3, the onset of action of antipyretics, 30-45 min. 4, small infants or other patients with fever over 39-40 ℃ (especially with obvious discomfort), should be timely symptomatic treatment. 5.Do not abuse antimicrobial agents when the etiology is unknown. 91% or more viral infections in children. 6, do not advocate the use of ice / alcohol for physical cooling. 7.Antipyretic drugs cannot prevent febrile convulsions nor should they be used prophylactically . 8.Continue to use only when the child shows discomfort, and consider changing to other drugs when the discomfort is not reduced. 9. Consider changing the medication only if the discomfort persists or if the discomfort reappears before the next dose of medication is due to be used (antipyretics are usually repeated at 6-8 hour intervals).