1, postmenopausal women are more prone to osteoporosis and the incidence of osteoporosis than men: osteoporosis is one of the main causes of bone pain, bone deformation, fractures, and its pathology is characterized by a decrease in bone mineral content calcium and bone matrix components in equal proportions, thinning of the bone cortex, reduction of bone trabeculae, thinning or even fracture. The bone growth process is shaped by two dynamic aspects: bone formation and bone resorption. Estrogen stimulates osteoblasts and inhibits osteoclasts, which make bone matrix. If estrogen levels decrease, osteoblast activity decreases and osteoclast activity increases, resulting in decreased bone formation and increased bone resorption. After the onset of menopause, the lack of estrogen increases the activation of some osteoclasts on the bone surface, accelerating bone formation and bone resorption, i.e., accelerated bone conversion, when bone resorption is greater than bone formation and bone loss. However, after menopause, especially 1-3 years after menopause, as the amount of estrogen in the body drops sharply, bone turnover is further accelerated and more bone is lost, if bone turnover is not inhibited, bone trabeculae gradually become thinner and osteoporosis occurs. The bone mass of men and women starts to decline after the age of 40, and women lose much more bone mass than men after menopause due to the sharp decline in the amount of estrogen in the body, so the incidence of women is much higher than that of men. 2, Chinese medicine theory and treatment: osteoporosis belongs to the category of “deficiency” in Chinese medicine, and “kidney deficiency” is the basic cause of the disease. According to the theory of Chinese medicine, “kidney is the origin of the innate nature and is the master of bone and marrow”, the kidney is treated with the method of tonifying the kidney, filling the essence, nourishing the marrow and activating the blood, in order to achieve the purpose of strengthening the muscles and bones of the peasants. The “kidney” in Chinese medicine has part of the endocrine function, especially the function of hypothalamus-pituitary-gonadal axis, so the kidney tonics can enhance the activity of osteoblasts and increase their number. The treatment of osteoporosis should be based on the principles of restoring bone mass, preventing continued bone loss and relieving symptoms. TCM treatment can be used to improve the antioxidant capacity, immune function, anti-apoptotic capacity and regulate the sex hormone level, to reduce the abnormal bone metabolism caused by multiple factors, especially the decrease of sex hormone level, in addition to the modern medical treatment of sex hormone therapy, calcium supplementation therapy and vitamin D supplementation therapy. To achieve the purpose of treatment of this disease. Chinese medicine treatment is considered from the perspective of the whole human body, which is both therapeutic and corrective, and is really beneficial to middle-aged and elderly people. It can relieve the clinical symptoms of osteoporosis, such as back pain, generalized bone pain and weakness, and can also improve the level of sex hormones and reduce the loss of bone calcium. At the same time, it can also improve the symptoms of aging and greatly improve the quality of life of middle-aged and elderly people. 3.Prevention: Develop a good diet and living habits to maintain the relative stability of bone mass and reduce its loss. Regular active exercise, appropriate load; avoid excessive smoking, cooking alcohol, taking too much caffeine, reasonable nutrition, higher intake of calcium, such as consumption of milk, soy products, fish, shrimp, crab. Long-term strict vegetarian or low-salt diet should pay more attention to calcium supplementation. Small doses of estrogen therapy can be considered for post-menopausal women.