It is confirmed by foreign studies that solid order can not only prevent the occurrence of bone metastasis related time, but also prolong the survival of patients; finally, I introduced some experiences of applying solid order to treat patients with bone metastasis in combination with clinical practice, endocrine therapy combined with solid order can significantly improve patients’ bone metastasis related response, and some patients showed disappearance of bone metastasis. Prof. Changling Li concluded that the incidence and mortality rate of prostate cancer in China has increased rapidly in recent years, and it has become the seventh most malignant tumor in men, and more than half of the clinically diagnosed prostate cancer patients in China have bone metastasis. We hope that Guerin can help more and more prostate cancer patients.