Liver cancer is a malignant tumor that occurs in the liver and includes both primary liver cancer and metastatic liver cancer. Relatively speaking, the mortality and incidence rate of liver cancer is not low. There are three conditions that can lead to the occurrence of liver cancer: 1. Hepatitis B virus is the biggest hidden danger that induces liver cancer. The way that hepatitis B virus triggers liver cancer is that the human body is infected with the virus, which is actively replicating in the body and causing damage to the liver, resulting in chronic hepatitis, and long-term chronic hepatitis leads to cirrhosis, which then develops into liver cancer. This process is long and takes more than ten years. 2. Secondly, biliary system diseases, such as liver and bile duct stones and liver fluke, can induce liver cancer. Although the etiology and pathogenesis of liver and biliary diseases are different, they affect each other at some levels and both may eventually lead to liver insufficiency and even chronic liver failure. 3. Fatty liver can also lead to liver cancer, and the incidence is on the rise. Severe steatohepatitis can also lead to cirrhosis, which can eventually develop into liver cancer. Doctor’s tip: The symptoms of liver disease are often atypical at the early stage of development, so patients often delay the time of treatment. Physical examination is an effective means to detect liver disease in time, and ordinary people should have a liver examination once a year. Hepatitis B virus carriers, cirrhosis patients, long-term alcoholics, and people with mildly elevated AFP are high-risk groups for liver cancer and should undergo ultrasound and AFP examination every six months even if they have no uncomfortable symptoms.