The first site of nephrogenic edema

Nephrogenic edema includes nephritic edema and nephrotic edema, with nephritic edema first appearing on the eyelids and nephrotic edema first appearing on both lower limbs and the tops of the feet. Nephrogenic edema is mainly caused by the reduced glomerular filtration rate and the inability to excrete water out of the body in a timely manner. This kind of edema has a great characteristic that it appears first in the areas with looser tissues, and the eyelids are such areas, so patients with nephritis first develop eyelid edema, in most cases after waking up from sleep. Nephrogenic edema is the opposite of nephrotic edema. Nephrogenic edema is caused by hypoproteinemia, and this edema is most often found in the lower parts of the body, so the most frequent areas are the lower extremities and the tops of the feet. From the site where the edema first appears, we can initially determine whether it is inflammatory or nephrotic edema. Since inflammatory edema is caused by a decrease in glomerular filtration rate, some diuretic drugs, such as torasemide, furosemide, etc., can be applied to relieve the symptoms of this edema. In contrast, nephrogenic edema relief requires albumin supplementation, and diuretic effect alone is relatively poor.