The herb is considered by Chinese medicine to be slightly bitter and cold in nature, and is used to treat various disorders caused by damp-heat and poison. Gout is caused by dampness, heat and toxicity in the joints, paralyzing the flow of Qi and blood in the meridians. On the one hand, it is difficult to completely evaporate the medicinal effect of the herb by just soaking it in water; on the other hand, the treatment of gout by Chinese medicine is not only the efficacy of a certain drug, but also the combination of different drugs according to a certain rule to play a therapeutic role together. Therefore, it is not recommended to treat gout by simply using the water of Bupleurum and Serpentine, but to combine related drugs on the basis of evidence-based treatment to play a joint role in the treatment of gout.