When a patient takes a report after a gastroscopy plus biopsy, sometimes they will see the words, “Enterochemical +”, which can be 1 + here, of course, or 2 or 3 +. What does this mean? Is it dangerous in any way? Some patients don’t take it seriously and don’t even think about it, thinking it is not important; others are overly nervous, thinking that intestinalization will definitely turn into gastric cancer. Both of these attitudes are not very appropriate. Here, I will introduce what exactly is intestinalization, and hope to give you a satisfactory answer. Intestinalization refers to the replacement of gastric mucosal glands by intestinal adenoid glands. + means that the intestinalized area accounts for less than 1/3 of the total area of the gland and surface epithelium; ++ means that it accounts for 1/3 to 2/3; ++++ means that it accounts for more than 2/3. There is no uniform standard regarding the typing of enterosis. There is a typology that intestinalization can be divided into 3 types: Type I is complete intestinalization, which contains Pan’s cells, cup cells and epithelial cells with absorption function. This type of intestinalization does not increase the risk of gastric cancer and is not a cause for concern. Type II enterosis is an incomplete enterosis containing a small number of absorptive cells, a small number of columnar cells in an intermediate form, and some cupped cells. Type III is an intermediate state between type I and type II, with features of both type I and type II. It has been analyzed that patients with type II or type III enterocytosis have an approximately 20-fold increased risk of developing gastric cancer. In a 5-year follow-up study, 42% of patients with type III intestinalization developed gastric cancer, suggesting that intestinalization is a precancerous lesion of gastric cancer. Therefore, we should not take enterolization lightly.