Many patients can not figure out how to get his kidney disease, in fact, the cause of kidney disease can be roughly divided into the following categories of description: 1, can not find the cause, called primary nephritis, in fact, there is a cause, that is, the body of the kidney tissue “heterogeneous antigen”, the immune system attacked it, causing an inflammatory response. 2, to find the cause, such as purpura nephritis, lupus nephritis, hepatitis B-related nephritis, drug allergic interstitial nephritis, etc.. 3, metabolic nephropathy, such as diabetic nephropathy, hyperlipidemia kidney damage, obesity nephropathy, uric acid nephropathy, etc. 4, vascular nephropathy, vascular stenosis (congenital or acquired) causing ischemic damage to the kidney. 5.Hereditary, with fewer cases.