Introduction to the types of commonly used immunosuppressive drugs and their combination scheme

  Immunosuppressive drugs, also known as immunosuppressants, are commonly known as anti-rejection drugs. In order to prevent the occurrence of transplant kidney rejection, kidney patients need to take immunosuppressive drugs for a long time, and usually they also need to combine 3 or even 4 immunosuppressive drugs, and it seems that the combination scheme among them also varies. So, kidney patients who have a strong desire to explore the unknown world must have muttered in their hearts a thousand times: How many kinds of oral immunosuppressive drugs have been marketed? Can we just put a few together and start eating them?  Now, Dr. Wang will talk about this topic with all kidney friends, but only a shallow 。。。。。。  There are many oral immunosuppressive drugs commonly used in clinical practice, so many that Dr. Wang does not have the time (lazy) to count how many kinds. However, Dr. Wang knows there are several categories! According to the mechanism of action of different drugs, they can be divided into the following categories: ① Adrenocorticosteroids: commonly used drugs include prednisone, prednisolone, Medrol, etc.; ② Calcium-regulated phosphatase inhibitors: commonly used drugs include cyclosporine A (neo-sandiamine, neo-serpine), tacrolimus (Pulcoflox-commonly known as FK506, Pulcoflox extended-release capsules, Zhongmei-Tacrolimus); ③ Antimetabolites or antiproliferative class: commonly used drugs include mycophenolate esters (primaquine, cyclobenzaprine, mif), purine analogs (azathioprine, imidazolibine); ④ other classes: such as sirolimus (rapamycin, etc.).  The topic of drug combination program is too professional and elaborate, Dr. Wang is deeply difficult to tell a roadmap in less than 10,000 words, so let’s say a simple, easy to remember basic principle: only one of the above four types of drugs in each category!  I hope the above information can meet the exploration feelings of some kidney friends!