Clinical manifestations of Guillain-Barré syndrome: symmetrical delayed paralysis of the limbs, peripheral sensory deficits with or without cranial nerve damage, may be accompanied by respiratory muscle paralysis, autonomic dysfunction, but sphincter function is mostly normal. Cerebrospinal fluid findings show protein cell separation in 2/3 of patients. Electromyography suggests slowing of nerve conduction velocity. Choice of treatment program 1.High-dose immunoglobulin intravenous injection; 2.Plasma replacement; 3.Neurotrophic agents; 4.Improvement of microcirculation; 5.Non-specific anti-inflammatory therapy; 6.Antimicrobial drugs; 7.Assisted respiration; 8.Sympathetic treatment and prevention of complications; 9.Rehabilitation therapy. Examination items during hospitalization 1. Necessary examination items: (1) blood routine, urine routine, stool routine; (2) liver and kidney function, electrolytes, blood glucose, blood sedimentation, blood gas analysis, coagulation quadruple test, blood type, tumor full test, immunity penta test + rheumatism triple test, infectious disease screening (hepatitis B, hepatitis C, syphilis, AIDS, etc.); (3) electrocardiogram, chest radiographs; (4) electromyography + nerve conduction velocity + F wave, H-reflex; (5) lumbar puncture: cerebrospinal fluid routine, biochemistry, smear to find bacteria, cerebrospinal fluid immunoglobulin test, puncture cytology pathology. (2) Campylobacter jejuni antibody, anti-GQ1b antibody test is feasible. (1) MRI of skull, MRI of cervical spine, MRI of thoracic spine, MRI of lumbar spine; (2) 24-hour ambulatory electrocardiogram, thoracic CT; (3) ultrasound of abdomen, abdominal CT. Selected medications (1) immunoglobulin infusion; (2) plasma exchange; (3) neurotrophic agents; (4) improve microcirculation; (5) non-specific drugs; (6) immunoglobulin; (7) immunoglobulin; (8) immunoglobulin; (9) immunoglobulin. Drugs; 5, non-specific anti-inflammatory treatment; 6, symptomatic treatment and prevention of complications of the relevant drugs. Discharge criteria: 1. Improvement or basic recovery of neurological deficit; 2. Stable condition after 2 weeks of treatment; 3. Effective control of complications. Variation and cause analysis 1, combined infection (lung, urinary tract, intestinal tract, etc.) during hospitalization, requiring anti-infection treatment, leading to prolonged hospitalization and increased costs; 2, patients may have respiratory muscle paralysis, requiring ventilator-assisted respiration, leading to prolonged hospitalization and increased costs; 3, patients may have circulatory dysfunctions (cardiac arrhythmia, low blood pressure, etc.) due to phycological neurological dysfunctions, digestive system dysfunction (intestinal paralysis, etc.), resulting in prolonged hospitalization and increased costs; 4. The patient’s condition is stable after treatment.