Immunotherapy Usage and Precautions

The mechanism of sublingual immunotherapy is to use allergen extracts sublingually, gradually increasing from very low to high concentrations, so that the body gradually adapts to the substance (allergen), thus gradually changing the body from a highly sensitive state to a hypersensitive or tolerant (non-sensitive) state to treat or control allergic diseases (reduce the use of drugs or no drugs, reduce the risk of recurrence of asthma, sinusitis, etc.). The risk of recurrence of asthma, sinusitis, etc.). This treatment can take 3 years or more. Although immunotherapy is generally safe, there may be some risks. (1) Allergic reactions: such as urticaria, angioneurotic edema, etc. In severe cases, anaphylaxis or acute asthma attacks may occur, mostly within 30 minutes after administration. (2) A small number of patients may experience transient or short term aggravation of the disease or related symptoms, if necessary, symptomatic treatment, generally with the treatment time will gradually reduce or disappear. (3) In a few cases, gastrointestinal discomfort, mild diarrhea, local rash, itching of the mouth and lips, etc. may occur. (4) General discomfort, headache, arthralgia, a few patients may feel fatigue and weakness after taking the drug. (5) Poor or ineffective treatment: No treatment measure can be 100% effective due to individual differences or other unknown reasons. Although immunotherapy is effective in most patients who can find the allergen, there are about 20% of patients who are ineffective. (6) Other unpredictable complications. Due to the limitations of the patient’s atopic constitution and the level of development of medicine itself, it is not possible to make an unprejudiced estimate of possible future occurrences. Please read the above risk warning carefully for you and your family. The drug composition is the same for vials 1, 2, 3, 4 and 5, but the concentration increases gradually. For children (<14 years old), place drops under the tongue, hold for 1 - 3 minutes and swallow. Administer once daily, just before bedtime. Usually administered at the same time of day. The usual dosage is divided into incremental and maintenance doses, with incremental doses of #1, #2, #3 and maintenance doses of #4. Adults: drop under the tongue, hold for 1 - 3 minutes and then swallow. Administer once daily, just before bedtime. Usually administered at the same time of day. The usual dosage is divided into incremental and maintenance dosage, incremental dosage is No.1, No.2, No.3, No.4 and maintenance dosage is No.5. Precautions】 1. This product must be used under the guidance of a physician. Any medication-related side effects found during use should be promptly communicated to the physician. 2. If antiviral or bacterial vaccinations are administered at the same time, vaccinations should be administered half a week after the most recent dose of dust mite drops. You can continue the treatment with dust mite drops two weeks after vaccination. 3. To avoid other allergic side effects, contact with disease-causing allergens and those substances that interact with disease-causing allergens should be avoided as much as possible during treatment, i.e. allergen control for living and working environment is important, which facilitates treatment completion and improves efficacy. 4.If there is any change in health status during the medication period, such as infection with infectious diseases, pregnancy, etc., the doctor should be informed in time, and it is recommended to prohibit alcohol consumption and avoid any abnormal overexertion. 5. If the composition of the allergens may change during administration due to the patient's sensitivity and differ from the original allergen composition, treatment should be restarted from the minimum concentration; the same applies to those patients who have used other products for immunotherapy. 6.Where there is an adverse reaction within 24 hours of administration, the dose should be reduced by 3 levels on the following day (or to the minimum dose on the following day if in an incremental period), and then gradually increased after tolerance. 7.If you stop taking the medicine for more than two weeks (maximum 4 weeks), for example, when you take it again after vaccination, reduce the dose by 3 levels or start from the minimum dose and then gradually increase; if you stop taking the medicine for more than 4 weeks and take it again, you should start from the minimum dose. 8.The medicine should be kept under shade, airtight and in a cool place (not more than 20 degrees). Please keep this product in a place where children cannot get it with their hands. 9.Multiple follow-ups, follow-ups and check-ups are needed, etc.