First, should not use drugs when using drugs About 80% of hepatitis B patients are hepatitis B virus carriers, especially children and teenagers, in the stage of immune tolerance, at this time for a variety of therapeutic response, a variety of therapeutic drugs can not achieve the desired effect, at this time a large number of drugs for treatment, not only a waste of money, but also to break the immune silence of the body, so that the liver function abnormalities, and sometimes this abnormality is recurring and difficult to heal the lingering. The following is a list of the most important things to know about the disease. Zhangqiu People’s Hospital Infectious Diseases Han Qingrong Second, the drug, with the wrong drug Many patients with hepatitis B liver function abnormalities, transaminases rise, should be the time of antiviral therapy, should use the appropriate antiviral drugs, but the use of anti-hepatic fibrosis drugs, which in turn aggravated the burden on the liver; cirrhosis ascites, should strengthen diuretic, supplemental albumin, but but with interferon and other antiviral drugs, resulting in further deterioration of liver function, the use of antiviral drugs, and so on. The result is a further deterioration of liver function. Third, too much medicine Chinese medicine treatment of hepatitis B is very common, some Chinese medicine prescription, individual medicine dose is too large, more than the national pharmacopoeia provisions of several times, such as neem dosage up to 20 grams, the bean root up to 30 g. These Chinese medicine overdosage, for the liver, the liver, the liver, the liver, the liver, the liver, the liver, the liver, the liver. The overdose of these herbs can cause significant liver damage, and it is not uncommon for patients to suffer from drug-related liver damage due to excessive dosage of herbs. For children, the dose must be accurate, the use of any drug treatment, need to be based on the number of kilograms of body weight, the conversion of the correct therapeutic dose. Fourth, the amount of medicine is too small The appropriate dose of interferon for the treatment of hepatitis B is 3 million to 6 million units / every other day, out of the concern about the adverse effects of interferon, many patients use the dose of small, and 3 million units / every other day the dose of the following, often can not play a therapeutic effect, but will delay the condition, and even produce drug resistance. Five, medication intermittent think up to take medication, can not think up to break the drug; work a busy, forget to take the drug; a business trip, and forget to take the drug, these problems occur from time to time, this intermittent medication, can not ensure that the drug in the blood constant and effective concentration, can not achieve the purpose of controlling the development of the disease. Insufficient course of treatment Antiviral treatment of hepatitis B requires a long time, a course of treatment at least half a year to one year, of which interferon course of treatment is at least half a year, lamivudine more than one year, if the course of treatment is too short, it can’t inhibit the role of the virus at all. The course of anti-hepatic fibrosis also needs a long time, for example, the use of compound danshen preparation, compound cordyceps preparation and so on, all need more than one year, short-term use, can’t play the role of softening the liver, degradation of liver fibrotic tissue purpose. Seven, stop medicine suddenly Once the program of treating hepatitis B is established, it should be adhered to seriously and cannot be stopped suddenly. After the course of treatment is completed, the medicine should be stopped gradually under the guidance of physician, and it cannot be stopped without authorization in the course of treatment, otherwise the condition will have recurrence and “rebound”, and the typical example in this respect is lamivudine, and quite a number of patients in the process of using lamivudine, less than the time of treatment, or less than the time of treatment, or less than the time of treatment. In the process of using lamivudine, many patients do not have the time for treatment, or less than the standard for stopping the drug, stopping the drug without authorization, resulting in recurrence of the disease, and in some cases, the disease suddenly worsened. Once the drug reaches the expected therapeutic effect, it should be gradually reduced until completely terminated to avoid drug dependence and accumulation of toxicity. For example, the enzyme-lowering drugs, such as biphenyl dibenzoate, itself does not have antiviral and protect the liver cell membrane, only play a simple role in lowering the aminotransferase, only auxiliary therapeutic effect, to be normalized liver function, should gradually reduce the amount of drugs, stop the drug in a timely manner, the long-term use of drugs, easy to produce drug-resistant and cover up the disease. Nine, change drugs at will Once the treatment plan for hepatitis B is established, it should be adhered to, with regular follow-up, monitoring the development of the disease, and should not be stopped halfway without authorization, or add drugs, change drugs, change drugs at will is easy to make the treatment complicated, and it is difficult to find the reasons and treatment methods. Ten, too many medications The treatment of medication needs to be less and more precise, not the more drugs eat, the sooner the condition will recover, many patients with hepatitis B use too much medication, too miscellaneous, for example, at the same time, oral and injection of a variety of enzyme-lowering medicines, once the drug is discontinued, the condition of the easy to appear “rebound”; some patients in the hospitalization of the use of drugs up to more than 20 kinds of drugs, plus the oral Chinese medicine Some patients use as many as 20 drugs during hospitalization, plus oral Chinese medicine compounding, more medicinal flavors, the chance of adverse drug reactions and drug antagonism greatly increased.