1.Liver transplantation (including living liver transplantation) Liver transplantation is to replace the whole liver to remove the hepatitis B virus, there are surgical risks, the cost is about 200,000-400,000, but it can cure hepatitis B and cirrhosis. 2. Artificial liver Artificial liver is to filter out the toxins from the blood in the body by means of plasma replacement, but it cannot synthesize the protein of the liver, and it costs about 10,000 each time and needs to be done several times a week. It can be used as a supportive treatment for acute liver failure or as a transitional treatment for the waiting period for liver transplantation. Until the acute liver function is restored or liver transplantation is performed. 3.Liver cell transplantation (including living liver cell transplantation) Liver cell transplantation does not replace the liver, some new liver cells are imported into the body. The risk of surgery is relatively small, and the cost is $20,000 each time, and it needs to be done several times a year. But after some time these cells can also be infected by the hepatitis B virus, leading to further deterioration of liver function. Note: Among these ways of treating liver failure, the recovery probability of drug-related hepatitis and acute fulminant liver failure treated by liver cell transplantation or artificial liver is relatively high, while liver failure in chronic hepatitis B is difficult to solve the underlying problem unless the whole liver is replaced.