It is possible to have intercourse with kidney disease. Sex does not have any special effect on kidney disease, as long as it is not too frequent. There are many kinds of kidney diseases, mainly including glomerulonephritis, nephrotic syndrome, renal insufficiency and so on. Therefore, if you have kidney disease, you should visit the nephrology department of the hospital to assess the specific situation of kidney disease, which can generally be assessed by checking urine routine, kidney function, kidney ultrasound, and 24-hour urine protein quantification. For those who have urine protein, ACEI/ARB drugs can be used to protect the kidneys to reduce urine protein if the kidney function is mild. For patients whose creatinine urea is already elevated, the main treatment is the integration of kidney disease, and oral urotropic pellets can also be used to reduce creatinine. For patients with large urine protein quantification, kidney puncture needs to be checked to clarify the specific pathological type, which usually requires treatment with hormones or immunosuppressants. Pay attention to the prevention of cold and flu, avoid overworking and staying up late to prevent the aggravation of kidney disease.