If you suffer from H. pylori infection, then you must formally take anti-H. pylori medication, usually antibiotics are taken half an hour after meals and the rest half an hour before meals, and its treatment takes 10 to 14 days. The treatment of H. pylori-associated disease usually requires a 4-combination drug therapy, which mainly consists of 2 drugs, proton pump inhibitors and bismuth, taken before meals. For the 2 antibiotics that are chosen to be taken after meals, oral medication is usually needed for about 10 to 14 days, and the treatment is reviewed for H. pylori conversion. After the failure of the first treatment, prolonging the time of taking the medication can not improve the eradication rate, you need to stop taking the medication for 3~6 months, change the antibiotics, and if necessary, do the drug sensitivity test and then treat again. About Helicobacter pylori-related diseases take medication time, each person’s is not necessarily the same, specific should also be based on the patient’s specific condition to analyze. It is recommended that patients go to the hospital in time. Drugs need to be used under the guidance of a professional physician, do not self-medicate arbitrarily.