Pediatric congenital heart disease (referred to as congenital heart disease) is a congenital malformation formed as a result of abnormal development of the heart blood vessels during the fetal period, and is the most common heart disease in children. It occurs mostly due to the abnormal development of the fetal heart during the first trimester of pregnancy due to viral infections, radioactive radiation, the effects of certain medications, lack of nutrition, and certain hereditary factors, resulting in pediatric congenital heart disease. Common congenital heart diseases include atrial septal defect, ventricular septal defect, tetralogy of Fallot, patent ductus arteriosus, and pulmonary valve stenosis. With the development of medical science, many congenital heart diseases can be treated with early surgery. Therefore, early detection of suspicious symptoms is the key, in order to timely examination, clear diagnosis, and take the necessary measures. Attention should be paid to the following symptoms: 1, the baby’s cry is low and hoarse; 2, shortness of breath, weak breastfeeding; 3, small appetite, poor growth and development; 4, pale, irritable, sweaty, purple lips after strenuous activities or crying; 5, weak resistance, prone to colds, bronchitis, and pneumonia and other illnesses, and it is not easy to recover from the disease. In recent years, the domestic diagnostic technology and surgical technology of congenital heart disease is developing rapidly, most of the pediatric congenital heart disease through surgical correction of the success rate has reached more than 95%. However, some children due to parental negligence, delay in seeking medical treatment, so that the condition has reached an advanced stage, or lost the opportunity for surgery, or complications of cardiopulmonary insufficiency, increasing the risk of surgery. In this regard, we remind parents: 1, as soon as possible to take their children to the hospital for examination, to clarify the nature and degree of cardiac malformation, to determine the appropriate age for surgery, so as not to hold the idea of “waiting for a little bit older before treatment”, delaying the condition. 2, for the heart murmur but asymptomatic children, should not be negligent, should be regular physical examination, including chest X-ray, electrocardiogram, in order to understand the changes of the murmur and cardiopulmonary load. Consider surgery if necessary to prevent complications such as endocarditis. 3. For children who need to wait for surgery due to age or other factors, it is important to prevent colds, cultivate the habit of brushing teeth, and maintain oral hygiene. Tooth decay and tonsillitis should be actively treated. If there is a prolonged fever that does not go away, consult a physician as soon as possible and avoid strenuous physical activities so as not to aggravate the burden on the heart and lungs.