Congenital heart disease is mainly caused by a disorder of heart development during fetal life (i.e., the period before birth in the mother’s body). Such causes of heart development disorders may be related to genetic and environmental factors. Genetic factors include genetic mutations, chromosomal aberrations and inborn metabolic defects; environmental factors include the mother’s cold during the third trimester of pregnancy, such as rubella virus, coxsackie virus infection, diabetes mellitus, alcoholism, exposure to radiation, teratogenic drugs, hypoxia in the plateau, and the age of the pregnant woman. The incidence rate of pediatric congenital heart disease is about 7 per 1,000 in China, which is one of the important factors affecting pediatric health. The severity of pediatric congenital heart disease is mainly related to different kinds of heart malformations, serious cases can die after birth, most of them gradually aggravate with the growth of day and age, and may lose the opportunity of treatment, leading to death. In fact, many congenital heart diseases are potentially completely curable if detected early. This shows the importance of early detection and early treatment of pediatric congenital heart disease. How can we detect pediatric congenital heart disease early? Here are some common manifestations of pediatric congenital heart disease. 1, cyanosis Commonly, the skin of cheeks, lips, extremities, finger (toe) nails are cyanotic or dark red, may be present after birth, or appear when crying, activity, or appear and worsen with age. 2. Breathing difficulties Breathing is significantly faster and more labored, and cannot move vigorously. In severe cases, there is dyspnea when the baby is quiet, or dyspnea when lying down, which is reduced when sitting. Although the baby is hungry and desperately wants to suck milk, the sucking of milk is interrupted by breathing difficulties and choking easily. 3.Growth retardation The growth and development of the heart malformation can be normal in light cases, but the malformation affects the growth and development of heavy cases, and growth retardation occurs, with height and weight lagging behind those of normal children, but generally the intelligence of children is not affected. 4, poor activity stamina Activity stamina is related to the severity of the disease, the lighter than normal children’s stamina when strenuous activity, the heavier the slight physical activity will feel fatigue, can not participate in sports activities. 5, prone to colds, pneumonia, repeated respiratory infections, repeated pneumonia, not easy to cure, relatively long duration of the disease. Often cough, runny nose, and even shortness of breath, hemoptysis, etc. 6, squatting Some children with cyanotic congenital heart disease feel fatigued when they are active, and like to squat on the ground to rest for a moment to stand up and move. Infants who do not walk like to take the position of lying on their side with their limbs flexed. 7, pestle finger Also known as drumstick finger. Children with cyanotic congenital heart disease have deformed fingers and toes with widened and thickened ends in the shape of drumsticks. 8, excessive sweating, edema Due to the presence of cardiac insufficiency, it is easy to sweat, and even lower limb edema, perineal edema, etc. There are various manifestations of congenital heart disease in pediatric patients. Once the possibility of congenital heart disease is suspected, the patient should go to the hospital promptly, and generally speaking, a color heart ultrasound examination can determine it. Currently, there are two types of treatment for congenital heart disease: surgical (open) treatment and interventional (non-open) treatment. The physician will use the appropriate method of treatment according to the specific condition. As long as congenital heart disease is detected and treated early, most patients with congenital heart disease can be completely cured.