Nocturnal paroxysmal dyspnea is commonly associated with asthma, coronary artery disease, heart failure and bronchitis. 1. Asthma: Including barometric pressure, air temperature, viral infections, mycoplasma infections and bacterial infections can easily trigger asthma attacks. Asthma may cause the patient to wheeze at night, shortness of breath, chest tightness, dyspnea, cough and other symptoms. 2. Coronary heart disease: factors leading to coronary heart disease are age, genetic hypertension, dyslipidemia, obesity, smoking and so on. Coronary heart disease can lead to paroxysmal shortness of breath and difficulty at night, angina pectoris, pressure and tightness in the chest and other symptoms. 3. Bronchitis: Bronchitis is a non-specific inflammation of the bronchial tubes caused by microbial infection, physical or chemical irritation. It often manifests itself in coughing, coughing and wheezing, shortness of breath, paroxysmal dyspnea at night and other discomforts. 4. Heart failure: patients with heart failure and pulmonary edema may have paroxysmal dyspnea at night, often accompanied by sitting breathing. If patients have the above symptoms, consult a doctor in time to avoid delay and prevent the condition from deteriorating. Follow the doctor’s instructions and standardize the treatment and medication under the doctor’s guidance.