Redness of the skin in the palm area may be related to chronic liver disease, eczema, contact dermatitis and other diseases, but also to changes in hormone secretion levels in the body, friction and other factors. 1. Chronic liver disease. Liver palm is one of the most common clinical manifestations of chronic liver disease, mainly manifested in the skin of the palm of the finger belly and the size of the skin between the fishes is reddish color changes, but also may appear spider nevus and other skin changes. 2. Eczema. Eczema is a chronic inflammatory skin disease, and a variety of internal and external factors related to stimulation, the acute phase will be manifested as local skin redness, and even erosion; chronic phase can be manifested as redness of the skin, as well as accompanied by peeling, itching discomfort. 3. Contact dermatitis. Due to local skin irritation or allergic reaction after contact with irritating or sensitizing substances, it can lead to local redness, swelling, itching, stinging and other manifestations. 4. Hormone secretion level change. During pregnancy, due to changes in estrogen levels, the body’s metabolism is enhanced, and some pregnant women may experience redness in the palms of their hands. 5. Palm redness caused by friction. Repeated friction will lead to local vasodilatation, which will be manifested as localized skin redness in the clinic. As the redness of the palms is related to a variety of factors, the specific situation needs to be analyzed by the doctor, combined with other clinical manifestations.