Liver cancer is the “king of cancer” and one of the most common malignant tumors in clinical practice. The global incidence rate is increasing year by year and has exceeded 626,000/year, ranking 5th among malignant tumors; death is close to 600,000/year, ranking 3rd among tumor-related deaths. Liver cancer is highly prevalent in China, and currently, the number of incidences in China accounts for about 55% of the global incidence; it ranks second after lung cancer in tumor-related deaths. The number of deaths due to liver cancer exceeds 100,000 each year. The surgical resection rate of middle and late stage liver cancer is only about 5%-10%, and the surgical mortality rate is over 10%. Patients need to suffer a lot of surgical pain and cost in treatment. With the rapid development of imaging technology, percutaneous imaging-guided tumor ablation (PIGTA), as a minimally invasive tumor treatment method, has been developing rapidly in recent years at home and abroad, and has gradually become one of the common means of non-surgical tumor treatment. PIGTA is a minimally invasive tumor treatment method that has been developed rapidly at home and abroad in recent years. Commonly used local ablation techniques: radio-frequency ablation, microwave ablation, laser ablation, cryoablation, chemical ablation (ethanol, ethanol-acetate ablation) and ultrasound ablation (high intensity ablation). and High intensity focused ultrasound (HIFU). What are the principles and characteristics of ultrasound-guided microwave ablation for liver cancer? With the features of clear image, non-invasive and radiation-free ultrasound and real-time direct monitoring, a special treatment needle (microwave antenna or microwave “tip”) is used to enter the liver tumor through skin puncture for treatment. The thermal effect of microwave needle is actually using the same principle of microwave oven to make liver cancer tissues reach a local temperature of over 70℃ within a few minutes, causing coagulative necrosis of tumor target tissues with little or no damage to surrounding tissues, thus achieving the purpose of “burning” tumor cells. The most important feature of this minimally invasive treatment is that it is less invasive and has less impact on the patient’s whole body. Microwave ablation treatment not only has no side effects such as hair loss, weakness, anorexia and decrease of white blood cells caused by radiotherapy and chemotherapy, but also has the effect of increasing the immunity of the body. 85% of liver cancer patients in China are combined with Shandong Provincial Hospital Oncology Center Ye Xin Liver cancer is the “king of cancer” and one of the most common malignant tumors in clinical practice, with the global incidence rate increasing year by year and has exceeded 626,000/year, ranking 5th among malignant tumors; death is close to 600,000/year, ranking 3rd among tumor-related deaths. Liver cancer is highly prevalent in China, and currently, the number of incidences in China accounts for about 55% of the global incidence; it ranks second after lung cancer in tumor-related deaths. The number of deaths due to liver cancer exceeds 100,000 each year. The surgical resection rate of middle and late stage liver cancer is only about 5%-10%, and the surgical mortality rate is over 10%. Patients need to suffer a lot of surgical pain and cost in treatment. With the rapid development of imaging technology, percutaneous imaging-guided tumor ablation (PIGTA), as a minimally invasive tumor treatment method, has been developing rapidly in recent years at home and abroad, and has gradually become one of the common means of non-surgical tumor treatment. PIGTA is a minimally invasive tumor treatment method that has been developed rapidly at home and abroad in recent years. Commonly used local ablation techniques: radio-frequency ablation, microwave ablation, laser ablation, cryoablation, chemical ablation (ethanol, ethanol-acetate ablation) and ultrasound ablation (high intensity ablation). and ultrasonic ablation (High intensity focused ultrasound-HIFU). What are the principles and characteristics of ultrasound-guided microwave ablation for liver cancer treatment? With the features of clear image, non-invasive and radiation-free ultrasound and real-time direct monitoring, a special treatment needle (microwave antenna or microwave “tip”) is used to enter the liver tumor through skin puncture for treatment. The thermal effect of microwave needle is actually using the same principle of microwave oven to make liver cancer tissues reach a local temperature of over 70℃ within a few minutes, causing coagulative necrosis of tumor target tissues with little or no damage to surrounding tissues, thus achieving the purpose of “burning” tumor cells. The most important feature of this minimally invasive treatment is that it is less invasive and has less impact on the patient’s whole body. Microwave ablation treatment not only has no side effects such as hair loss, weakness, anorexia and decrease of white blood cells caused by radiotherapy and chemotherapy, but also has the effect of increasing the immunity of the body. In China, 85% of liver cancer patients have combined Case 2, male, 46 years old, right liver cancer.