Waking anesthesia is the gold standard for locating functional brain areas: Waking surgery is performed under anesthesia monitoring (to make the patient as comfortable and painless as possible), waking the patient at any time during the surgery as needed or keeping the patient awake throughout the surgery, observing the patient’s motor and speech functions while operating, and avoiding permanent disability due to surgical injury to important functional brain areas. Methods to protect brain function: 1. Electrically stimulate the brain tissue in the surgical field to identify brain areas (functional areas) that can cause temporary dysfunction, thus avoiding the location of the corresponding functional areas. For example, if the patient is awakened and asked to count or shown pictures to name, while the brain tissue is electrically stimulated, and if the counting is interrupted or naming is not possible after a certain place is stimulated, then this area is marked as a different functional area of language and needs to be properly protected. 2, while removing the lesion while allowing the patient to perform language and motor tasks, for example, while operating and communicating with the patient verbally, during the process of removing the lesion suddenly found that the speech is not fluent indicates that the surgical operation is adjacent to the language function area, and should be stopped in time. Or let the patient move the contralateral limb (or a part of it) during resection, if there is a delay or inability to move then the operation needs to be stopped to protect the function. Intraoperative magnetic resonance combined with functional neurological navigation is currently the best method to protect brain function and improve lesion resection by non-invasive means: 1. Functional neurological navigation uses preoperative structural and functional images to assist in determining the surgical approach and locating the target area. Intraoperative navigation is used to identify important anatomical structures such as the central sulcus. It helps to assist in locating functional areas and can be combined with cortical somatosensory evoked potentials to locate the central sulcus; motor evoked potentials monitor motor areas. 2. Intraoperative magnetic resonance can correct brain shift, update navigation in real time, determine whether tumors remain and show the relationship between functional areas, fiber tracts and the location of residual lesions, and its helps to improve the extent of glioma resection. The integration of both techniques, awake anesthesia and intraoperative MRI, is currently the first choice for maximizing safe resection of functional area gliomas. It is worth mentioning that despite the many advantages of awake craniotomy, not all patients are suitable for such a procedure option. Only patients with special tumor location, in order not to seriously affect his brain function, choose this approach. As long as the conventional general anesthesia surgical approach achieves maximum safe resection, the conventional surgery (intraoperative MRI combined with functional neurological navigation) is still the choice. Therefore all you need to do is to listen to your doctor and take the most optimal multimodal surgical aid that suits you.