PSA testing should be performed every 1 month after endocrine therapy, which is a basic monitoring tool for prostate cancer. The duration of PSA monitoring can be appropriately extended to 3 months when PSA drops to the lowest point. Anti-androgen drugs have an effect on liver function, so liver function should be paid attention to during treatment. Liver function should be tested monthly for the first 3 months after the start of treatment, and every 3-6 months thereafter. If the serum PSA continues to rise or if bone pain develops, a bone scan should be performed to determine whether bone metastases have occurred. In addition, androgen deprivation therapy can cause a series of corresponding complications due to a significant decrease in blood testosterone levels, such as hot flashes, decreased libido, erectile dysfunction, gynecomastia and decreased bone density, and can also cause an increased incidence of insulin resistance, arterial stiffness, diabetes mellitus and metabolic syndrome, and it is recommended that an internist be consulted for evaluation and treatment if necessary.