Since acne occurs mainly on the face and has a long course of treatment, patients are prone to the situation of seeking medical help in a hurry and being confused by some false advertisements for acne removal products. However, most of these products contain ingredients such as keratin strippers and glucocorticoids. Long-term use of keratin strippers can damage the integrity of the stratum corneum, and glucocorticoids can inhibit the synthesis of lipids in the stratum corneum, thus damaging the skin barrier; external rubbing of some herbs or herbal medicines made of alcohol can also damage the skin barrier. The high concentration of alcohol has high volatility, which will take away the heat from the skin and also the water on the skin surface, while alcohol has lipid solubility, which can weaken the skin barrier function and increase the permeability of the skin.