Recently, a series of patients who had their teeth extracted because of toothache came to my psychological clinic, which attracted my attention. The main reason for me to write this story is to warn all patients with toothache in the world that when you have unexplained toothache and when you cannot get effective treatment in dentistry, you should not easily extract your “painful” teeth. “You may want to have psychological counseling before deciding to extract the tooth. What I remember vividly was a middle-aged woman in her fifties, with a deflated mouth looking much older than her actual age. Seeing the patient’s helpless expression and her spitting words looked so strained, her husband standing beside her told me heartbreakingly that because she felt the toothache was unbearable, she now had all her teeth pulled out of her mouth, and although her teeth were gone but her cavity was so painful that she simply could not have dentures or eat anything, and she was now so anxious She was so anxious that she had a death wish. When I asked her why she came here for treatment of her toothache, she slowly began to tell me about her symptoms and the results of her treatment, and with tears in her eyes, she told me that she had a deep relationship with her brother since she was a child, and her brother spoiled her very much when she was a child, leaving her everything delicious to eat. When the doctor asked me which tooth was hurting, I couldn’t tell myself which tooth was hurting when the doctor knocked on it, but the doctor didn’t find anything wrong with the tooth. Then I was prescribed some painkillers, and the toothache symptoms did not improve at all after taking the medicine. The doctor in Shanghai also said that there was no problem with the teeth, but why did the teeth keep hurting? I asked the doctor in Shanghai, but the doctor did not prescribe any medicine, but only told me to go to the local psychological counseling department to see. But I don’t know why, after the extraction, I can’t touch the tooth bed, and I feel more pain, the pain can’t be described in words, it’s really painful, now I can’t sleep almost all night, and I can’t eat, I feel completely desperate 。。。。。。 After listening to her description, I have a clear understanding of her condition. It is easy to see that her toothache is closely related to her emotions, and what causes her emotions to change is related to her psychological factors (sudden car accident of her brother, with whom she has had deep feelings since childhood). Depression and anxiety itself can manifest as somatic discomfort, e.g., anxiety can manifest as heartburn and chest tightness, while others can manifest as stomach bloating, increased blood pressure, chronic pain, etc., and somatic discomfort can also exacerbate mood changes. In this middle-aged woman I used mood-improving medication and her toothache improved quickly. As the saying goes, toothache is not a disease but a pain that kills. Generally speaking, oral diseases such as tooth decay, gum inflammation and pulpitis are the most important causes of toothache, and when unexplained toothache occurs, the possibility of the existence of mental illness cannot be ignored.