Chronic fatigue syndrome” refers to a group of syndromes that are different from severe depression, drug dependence, bipolar disorder, mental illness and eating disorders. Its high prevalence of people are mainly mental workers, they do not know how to effectively relieve after the intense and busy work, so that the body is under great stress for a long time. The physiological and psychological stress defense mechanisms in the body, driven by strong will power, are overloaded and can no longer form an effective buffer after a long time. The syndrome is likely to appear under some unnoticed triggers. Some people who initially experience fatigue, burnout, and impaired memory and concentration often fail to recognize the disorder. They think the condition will be fine after a couple of days of sleep and rest, so they let their guard down. However, when the above-mentioned methods fail to relieve the condition, the symptoms often become severe, and by the time the individual finally seeks help from a professional psychotherapy institution, he or she has already suffered for a long time and has done corresponding damage to his or her mind and body. Therefore, many people who work mainly in the brain should be more aware of the syndrome and try to identify themselves in the early stages of the disease. The main manifestation of the syndrome is unexplained severe fatigue that lasts for several months, with clear episodes, and this state is not due to continuous work. Rest does not alleviate it and can have an impact on the social functioning of the person experiencing the attack. Some may experience memory loss or inability to concentrate, and dizziness and fatigue after sleep that is “worse than if they had not slept at all. Some individuals may experience significant discomfort after normal intensity work that does not resolve completely on its own for more than 24 hours. Some individuals also experience physical symptoms such as sore throat, swollen lymph nodes, muscle aches, multiple joint pains, and various types of headaches. For the above situation, our intervention suggestions are: 1. Individuals should have a proper assessment of their working hours and work intensity, and insist on working below the safety line. Once the working time and intensity of work exceeds their usual assessment standards, they should remind themselves to pay attention to rest in time. 2, regular physical examination of their own body, to exclude the possibility of various diseases. Ensure that they work in a healthy physical condition. 3, the combination of work and rest is a cliché relaxation concept. 7 plus 1 is greater than 8 theory also applies to adults (educational psychology that: 7 hours of study plus 1 hour of exercise exceeds the efficiency of 8 consecutive hours of study). 4. Diversification of life is an effective way to reduce stress, and doing something you are interested in after work will make relaxation more complete! Finally, if you feel that you can’t relieve your fatigue and sluggishness through self-regulation, please go to a professional medical institution for help.