High creatinine belongs to the concept of western medicine and creatinine value usually measures kidney function. Generally, high creatinine value indicates the presence of kidney failure, renal insufficiency and other diseases. Kidney yin deficiency and kidney yang deficiency belong to the category of traditional Chinese medicine, creatinine value and kidney yang deficiency or kidney yin deficiency is not yet a clear link, it is recommended to combine with the systemic symptoms to determine a clear pattern. 1. Kidney yang deficiency: coldness of waist and knees, fatigue, cold limbs, more so in the lower limbs, 晄white or sallow complexion; frigidity of libido, impotence and spermatorrhea in men, infertility in women with uterine cold, and clear leukorrhea; diarrhea and undigested food in stools or diarrhea in the five days of the week (pre-dawn diarrhea), long and clear urination, and polyuria at night. Kidney yang deficiency can be treated with Jin Gui Ren Qi Pills and Yu Gui Pills under the guidance of a doctor. 2. Kidney yin deficiency: pain in the lumbar and knee areas, dizziness, tinnitus, insomnia, thinness, hot flashes (a burst of heat), night sweating (abnormal sweating after going to sleep, but sweating stops after waking up), heart-heat (heat in the heart of the hands and feet, and self-consciousness of the heart and chest), and dryness of the throat. Kidney Yin deficiency can be treated with Liu Wei Di Huang Pill and Zuo Gui Wan under doctor’s guidance. If people with high creatinine want to determine whether it is Kidney Yang deficiency, Kidney Yin deficiency or other syndromes, it is recommended to combine with the systemic symptoms to clarify the syndromes and carry out the treatment under the guidance of a professional doctor’s diagnosis.