1. Do craniopharyngioma and pituitary tumor present with different symptoms? A: The clinical manifestations of craniopharyngioma and pituitary tumor are very similar, but the age of onset and imaging manifestations of patients are different. Generally speaking, craniopharyngioma is more common in children, while pituitary tumor is rarely seen in children; pituitary tumor is more common in adults, and the incidence of pituitary tumor is significantly higher than that of craniopharyngioma. 2.What is the difference between the two in terms of tumor growth site? A: The growth site of craniopharyngioma and pituitary tumor of subsaddle septal type is the same, while the growth site of craniopharyngioma and pituitary tumor of suprasaddle septal type is different. 3.Is there any difference between the positive indicators of blood biochemical examination of the two? A: Basically, they are the same, mainly: low thyroid hormone, low gonadotropin, low corticosteroid, etc. 4.How to distinguish craniopharyngioma and pituitary tumor? Can skull base CT differentiate craniopharyngioma and pituitary tumor? A: The differentiation of these two tumors mainly relies on cranial CT and MRI examination. Pituitary tumors are solid tumors with minimal calcification and tumor cystic changes, while craniopharyngioma has a calcification rate of over 90% and enamel craniopharyngioma has a cystic change rate of almost 100%. An experienced neurosurgeon can distinguish these two tumors from each other from imaging films. 5.Can CT of skull base confirm the diagnosis of craniopharyngioma? Is it still necessary to do pathological tissue examination? A: Experienced doctors can rely on cranial CT to diagnose craniopharyngioma, but this diagnosis is a clinical diagnosis, not a final diagnosis. The final diagnosis should be made by pathological examination after removal of the tumor, which is the final method to confirm all tumors. 6.What other tests are needed to diagnose craniopharyngioma? A: The main methods for preoperative diagnosis of craniopharyngioma are: cranial CT and MRI, hypothalamic-pituitary endocrine examination, and visual field examination.