Craniopharyngioma is a benign congenital tumor that occurs from the remnant tissue of the craniopharyngeal duct during embryonic life. The incidence of craniopharyngioma accounts for approximately 4% of intracranial tumors. However, it is the most common congenital tumor in children, accounting for the first of all saddle area tumors. The disease can occur at any age, but 70% occur in children and adolescents under the age of 15. Craniopharyngioma, also known as pituitary duct tumor, is a benign congenital tumor that occurs in the remnants of the craniopharyngeal duct during embryonic period, accounting for about 4% of intracranial tumors and the first of saddle area tumors. The clinical manifestations of craniopharyngioma include the following aspects: 1. Symptoms of increased intracranial pressure, generally due to the development of tumor to the saddle involving the anterior half of the third ventricle. The occlusion of interventricular foramen leads to hydrocephalus. 2.Visual field impairment, caused by the tumor located in the suprasellar area compressing the optic nerve, optic cross and optic tract. 3.Pituitary hypoplasia. The tumor compresses the anterior pituitary gland and causes growth disorder due to insufficient secretion of growth hormone and gonadotropin, and adults may have hypogonadism and amenorrhea. 4. Hypothalamic damage: Hypothalamic compression by tumor development to the saddle may manifest as hypothermia, drowsiness, uremia and obesity reproductive incompetence syndrome. Treatment of craniopharyngioma: Surgery is the main treatment for craniopharyngioma. Early diagnosis, use of microsurgical techniques, striving for the first total surgical resection, strengthening hormone replacement therapy and postoperative monitoring are important to improve the efficacy. Since the tumor is closely attached to the hypothalamus and important surrounding neurovascular, total resection is sometimes difficult. The tumor is prone to recurrence, and the risk of re-opening surgery is high and traumatic. For recurrent craniopharyngioma, stereotactic cystic fluid aspiration + internal radiotherapy/gamma knife treatment can be chosen. This method has the advantages of less trauma, lower risk, lower cost and faster recovery, which is a good method for recurrent craniopharyngioma treatment at present.