Craniopharyngioma originates from the residual flat epithelial cells during pituitary embryogenesis, and is a common congenital benign intracranial tumor, mostly located above the pterygoid saddle, and a few in the saddle. Postoperative care for children with craniopharyngioma: 1, postoperative attention to electrolyte and acid-base balance of children with craniopharyngioma As children are generally fasted and dehydrated after surgery, which can easily lead to electrolyte disorders, therefore, postoperative rehydration should be given in time to strengthen the nutrition, measurement of electrolytes, blood gas analysis, so that the partial pressure of blood oxygen and CO2, blood potassium, blood sodium, blood calcium, blood chlorine, blood glucose to maintain at the normal level. 2.Postoperative prevention of respiratory infection in pediatric patients with craniopharyngioma In order to prevent respiratory infection, the respiratory tract should be kept unobstructed after operation. Children’s postoperative reaction has certain characteristics, generally they are afraid of wound pain and unwilling to cough after operation, nursing staff should induce or perform stimulation to cause children’s coughing, and change position frequently, pat the back to help children cough out sputum, and give suction when necessary. 3.Children with craniopharyngioma should have postoperative epilepsy. Epilepsy is a common complication of craniocerebral surgery, clinical care should closely observe whether there is any aura of epilepsy, avoid children’s activities alone to prevent accidents. Actively remove all triggering factors, provide a quiet and comfortable ward environment, and let the child rest quietly in bed to reduce oxygen consumption. For children with epilepsy, in addition to the routine administration of antiepileptic drugs, give low-flow oxygen to prevent brain tissue hypoxia. For restlessness, convulsions, should be given sedative, antispasmodic drugs, as soon as possible to control the symptoms. Warm tips: craniopharyngioma is very harmful to children, parents once found that the child has abnormal symptoms timely treatment, so as not to cause serious consequences.