For craniopharyngioma surgery, if the patient is generally in good condition, the preferred treatment is total resection of the tumor. If the tumor is closely adherent to the internal carotid artery, optic nerve and other surrounding tissues, or if the tumor infiltrates the hypothalamus, even if it is barely removed, the result may not be satisfactory. There are various surgical approaches, such as inferior frontal approach, pterygoid point approach, endplate approach, intercallosal vault approach or transcortical lateral ventricular approach, transsphenoidal sinus approach, combined approach, etc. Radiotherapy is considered an effective adjunct to subtotal resection of the primary tumor and treatment of recurrent tumors. Due to the benign nature of craniopharyngioma and the inherent side effects of radiotherapy, most physicians do not recommend radiotherapy for patients with total tumor resection. However, for surgical residual tumors, radiotherapy should be considered. The dose of conventional external radiation therapy is not easy to master, and it is difficult to control the recurrence and avoid or reduce the brain damage caused by radiotherapy. If the dose of radiotherapy exceeds 55Gy, the effect of inhibiting tumor recurrence is not only not significantly improved, but also increases the possibility of delayed toxic reactions. It has been reported in the literature that for children who received radiotherapy, 32%-33% of them had to receive special education due to reduced learning ability. Other complications of radiotherapy include radiation-induced tumor formation (e.g., glioblastoma, sarcoma, meningioma), radiation brain necrosis, radiation vascular occlusion, radiation vascular inflammation, optic neuritis, dementia, subbasal ganglia calcification, thalamic-pituitary dysfunction, and hypothalamic obesity.