Lumbar puncture is a common procedure for children with leukemia, but for a parent of a first-time leukemia patient, there are always many concerns and worries when they first learn that their child is going to have a lumbar puncture, so today we will talk about what lumbar puncture is all about. Why do I need a lumbar puncture? Lumbar puncture has two main purposes: first, to check the cerebrospinal fluid for abnormalities and determine whether there is central nervous system leukemia (commonly known as “cerebral white”); second, to prevent central nervous system leukemia by prophylactic intrathecal injection of chemotherapy drugs (commonly known as “playing sheath”). Sheathing is an important treatment option for children who already have leukoencephalopathy. Is lumbar puncture dangerous? Lumbar puncture is a relatively safe routine in pediatrics and is usually not dangerous when performed by a physician in strict accordance with the protocol. Some of the risks that may be seen include bleeding at the puncture site, damage to the nerve roots and bone marrow during the puncture, neuralgia, failure of the puncture, headache and vomiting after the puncture. What are the decisive factors to ensure a successful lumbar puncture? In fact, there are many factors that determine whether a lumbar puncture goes well or not. The three main factors are: the child’s position, the needle technique, and the depth of the needle. In our ward, parents are asked to assist the doctor in positioning the child (sometimes parental encouragement and companionship can greatly reduce the child’s fear and anxiety), making sure that the child is placed in a left-sided, bent-knee position, allowing the child’s waist to bend to the maximum extent, while securing the child. For pediatric hematologists, this is also a technical task, and striving to complete this operation in the shortest possible time and with the least amount of damage is also something that requires constant training and improvement on the part of the physicians. What are the precautions after lumbar puncture sheathing? After the lumbar puncture, the child should lie flat on the pillow for 4 to 6 hours (without pillow) to avoid headache. If there is any postoperative discomfort such as headache or vomiting, report it to the doctor in charge.