Glomerulonephritis and tubulonephritis have different triggering causes, different clinical manifestations, and different treatment plans. Glomerulonephritis is mostly caused by acute streptococcal infection, manifested by large amount of proteinuria, increased foam in urine, 24-hour urine protein quantification greater than 1g, treatment is anti-streptococcal treatment, can be intravenous drip penicillin. Renal tubulointerstitial nephritis is mostly caused by the application of kidney-damaging drugs, such as the application of gentamicin. Antipyretic drugs can all cause acute tubulointerstitial nephritis, clinical manifestations are increased nocturia, nighttime rise greater than 3 times, 24-hour urine protein quantification less than 1g, treatment plan can be short-term application of hormones, routine application of 20mg methylprednisolone or prednisone acetate for 3-5 days.