On April 17, Warren Buffett wrote to shareholders of his investment company that he had been diagnosed with prostate cancer, and the term “prostate cancer” immediately became an Internet buzzword. Is there a high incidence of prostate cancer? Is it dangerous? Is it easy to cure? It has attracted more attention than ever before. The incidence of prostate cancer is the second highest among all malignant tumors in men worldwide, with significant geographic and racial differences, with the highest incidence in Australia, New Zealand, the Caribbean and Scandinavia, and lower incidence in Asia and North Africa. The incidence of prostate cancer in the United States ranks first among tumors that are harmful to men’s health, with 32,050 deaths from this disease in 2010. The incidence of prostate cancer in Asia is much lower than that in Europe and the United States, however, the trend is rapidly increasing in recent years. According to the statistics in Shanghai, China, prostate cancer has overtaken bladder cancer to become the first urological tumor in men since 2000. Yang Tiejun, Department of Urology, Henan Cancer Hospital, prostate cancer is mainly in older men, with a median age of 72 years for newly diagnosed patients and a peak age of 75-79 years. The risk factors that cause prostate cancer are: genetics, high animal fat diet, lack of exercise, etc. Compared with liver cancer and stomach cancer, prostate cancer is more “gentle” and most cases progress slowly, but early prostate cancer is usually asymptomatic, so it is called “the invisible killer of older men” by urologists. The tumor invades the urethra and bladder neck and causes symptoms similar to lower urinary tract obstruction or irritation, but is still often mistaken for prostate enlargement and inflammation by patients or primary care physicians. As the disease continues to develop, acute and chronic urinary retention, hematuria, and urinary incontinence occur. Advanced patients often have complications with bone metastases, which manifest as bone pain, pathological fractures, anemia, and spinal cord compression leading to lower limb paralysis. In fact, it is not difficult to detect prostate cancer. Rectal examination combined with PSA examination is currently recognized as the best primary screening method for early detection of prostate cancer. Further examination of suspected patients with transrectal ultrasound and, if necessary, systematic puncture biopsy of the prostate can confirm the diagnosis. If prostate cancer is detected early and with reasonable treatment, most patients can be cured. The efficacy of treatment for progressive prostate cancer is also clear and can prolong the survival time and improve the quality of life of patients. However, many patients in China are not detected in time and often find the culprit only after severe bone pain or even fracture leading to paralysis, missing the best time for treatment. Therefore, urologists urge older men to be alert to prostate cancer, and the American Urological Association (AUA) and the American Society of Clinical Oncology (ASCO) recommend that men over the age of 50 receive routine annual rectal examinations and PSA tests. Warren Buffett, the “God of Stocks,” calls his prostate cancer early, perhaps thanks to his health care provider’s awareness and vigilance of the disease, and is therefore optimistic about the outcome of treatment.