In the early stage of kidney disease, you often do not feel pain, so it is easy to be ignored and hard to find. Many patients are very uncomfortable before they go to the hospital, only to find that the kidney disease is already very serious and even life-threatening, requiring immediate hemodialysis. Therefore, the United States “Health” website article reminds that the following 10 common signals must be very alert. 1, no energy: when the kidney function is not good, many wastes are difficult to excrete from the urine, there will be mental weakness, fatigue, weakness and other feelings of no energy. Kidney disease, protein and other nutrients leak from the kidneys, through the urine out of the body, there will also be no energy performance. Some patients will think that they are overworked, or other reasons, and ignore the kidney problems. 2, poor appetite: Patients will have a variety of digestive symptoms, especially because of edema in the gastrointestinal tract, often not thinking about eating, bloating and other symptoms of digestive disorders. 3, nausea and vomiting: When renal failure occurs in diabetic patients, the urea nitrogen in the blood increases, and the urease enzyme of bacteria in the intestine will break down urea into ammonia, which can stimulate the mucosa of the gastrointestinal tract and cause nausea and vomiting. In addition, the kidney’s concentration function of urine is reduced at this time, which will increase the amount of nocturnal urine of patients, while the body will lose a lot of water at night, blood concentration, and the blood urea nitrogen level is relatively higher in the morning. Therefore, it is easy to increase nausea and vomiting in the morning. 4, foam in urine: there are many reasons for foam in urine, and kidney disease can also trigger this phenomenon. If protein leaks from the kidneys into the urine, the urine will foam a lot. 5.Urine volume is not normal: Healthy people urinate about 4~6 times a day, and the volume of urine is about 800~2000ml, if the number of times and volume of urine is too much or too little, you should pay attention to it. 6, urine protein and urine occult blood: protein or occult blood in urine is an important indication of kidney disease, which can be detected by urine routine. However, sometimes non-nephrologists may ignore this point, so it is better to consult with a nephrologist. 7.Anemia: Patients with anemia often go to hematology department. In fact, in addition to the function of excreting waste products and other functions, the kidneys also have the function of secreting hematopoietic hormones, which is also a big signal of kidney function damage. 8, hypertension: Hypertension can cause hypertensive nephropathy, also known as hypertensive kidney damage, so people with hypertensive disease should pay more attention. Of course, kidney disease can also lead to hypertension. 9. Gout and hyperuricemia: Gout and hyperuricemia are caused by too much uric acid in the blood. In people with high blood uric acid, uric acid will be deposited in the kidneys and make the kidney function impaired. 10. urinary tract infection: People who often have urinary tract infections, over time, may cause kidney insufficiency. If the above symptoms appear, you should be diagnosed in time, with a view to early detection of kidney disease and thus early treatment.