Diabetes mellitus is a common disease, especially in the elderly population. With a long history of diabetes and poor glycemic control, diabetic neurological and vascular lesions can develop later in life. One typical manifestation is diabetic foot. Patients gradually develop numbness from the toes, darkening, pain, skin necrosis, and even rotting of the toes. Severe cases require amputation treatment to prevent systemic infection. If this occurs, in addition to regular blood sugar control, slowing down the rapid development of the lesion plus medication to control pain and anxiety, there are some good ways to further improve the patient’s quality of life, such as: 1, minimally invasive techniques under lumbar sympathetic nerve block or destruction to improve blood circulation in the lower limbs and slow down the development of the disease. 2, diabetic foot ozone sleeve therapy. Reduce inflammation and pain, delay the aggravation of the disease and accelerate wound healing.