In order to prevent adverse reactions and complications of hormones and avoid blind or inappropriate use of hormones, the following points should be noted: 1. The indications and contraindications for the use of corticosteroids should be strictly controlled. In general, osteoarthritis and ankylosing spondylitis patients should not use hormones, infectious, tuberculous arthritis and tumor neck, shoulder and back pain prohibit hormones. 2, to strictly control the dose and course of treatment, to minimize the adverse effects of hormones. If the hormone dose is large and the time is long, antispasmodics, alkaline drugs and anticholinergic drugs should be used together, especially for those with a history of peptic ulcer. 3. The dose should be gradually reduced after the symptoms are controlled, and the drug should not be stopped suddenly, or other drugs should be used instead during its treatment. Otherwise, the original symptoms may recur or worsen, and even adrenocortical insufficiency syndrome may occur. 4, to start the application of hormone treatment of rheumatoid arthritis, should be combined with Ryder, penicillamine or other drugs that change the course of the disease, and should be used for more than 1 year to control the development of rheumatoid arthritis, to prevent relapse after discontinuation of hormones. 5. To prevent proliferation or infection. For those who already have infection, while applying hormone therapy, effective antimicrobial agents must be used at the same time; also be alert to serious mycobacterial secondary infection. 6.To take low salt or salt-free diet during hormone therapy, and regularly observe blood pressure, blood potassium, blood sugar and urine sugar. Hypokalemia should be prevented from occurring. Supplement potassium chloride when necessary. 7. To apply hormone for a long time in elderly boilers, special attention should be paid to the phenomenon of protein catabolism, such as osteoporosis and pathological fracture. If necessary, testosterone propionate or nandrolone phenylpropionate should be given at the same time to stop or delay the occurrence of this phenomenon. Calcium tablets and vitamin A and D pills should also be supplemented opportunistically. In conclusion, health care professionals and patients with neck, shoulder and back pain should always remember this phrase: Hormones have risks and should be used with caution!