The dosage of rhGH and the course of treatment vary according to the type of disease, age at the time of treatment and bone age. Compared with foreign countries, the current general situation in China is that the dosage is slightly lower and the course of treatment is slightly shorter. Recommended reference dosage: Complete GHD: 0.1~0.12u/kg/d for preschool and school-age children Partial GHD: 0.12~0.15u/kg/d for pre-pubertal children, and increase the dosage appropriately starting from puberty, and it can be up to 0.15u/kg/d or greater by puberty. For other diseases such as ISS, SGA, TS, etc., the starting dosage is about 0.15~0.2u/kg/d, usually not more than 0.2u/kg/d. Parents of children often ask how long the growth hormone should be used. In fact, the course of treatment varies from disease to disease, and the doctor will take into consideration the degree of the child’s height deficiency, the development of epiphyses, the willingness of the child and the parents, and the family’s financial situation, etc., and make the decision at the same time. The doctor will decide. However, it is generally recommended that the duration of treatment should not be less than one year, otherwise, the duration of treatment will be too short and the increase in lifelong height will be too small to be of any significance. If the child’s family economic conditions permit, the height is persistently lower than the normal height of children of the same age, and the epiphysis has not closed, the growth hormone can be continued until the late pubertal period when the growth rate of height is retarded (annual height growth of less than 1~2 cm), then discontinue use of the hormone.