Recurrent attacks of gallbladder stones and cholecystitis seriously affect the quality of life of patients. Laparoscopic cholecystectomy has become the “gold standard” for the surgical treatment of benign gallbladder diseases because of its small trauma, quick recovery and short hospital stay. Minimally invasive is the development direction of surgical treatment, and how to reduce the trauma to the minimum during the surgical operation is the hot spot of future research in general surgery. Umbilical single-port laparoscopic cholecystectomy uses a single incision, which is relatively less invasive than the traditional four-port or three-port surgical approach. The skin of the umbilicus is thin and soft, and the natural folds of the umbilicus are used to make the incision, so there is no visible scar and no tension after suturing, which greatly reduces the pain of the incision. The recovery time of the gastrointestinal tract, the time of resuming normal diet, and the hospital stay after surgery are greatly reduced. In conclusion, transumbilical single-port laparoscopic cholecystectomy for the treatment of cholecystitis is less traumatic, less bleeding, faster recovery, and fewer postoperative complications, and transumbilical single-port laparoscopic cholecystectomy has been carried out in our hepatobiliary surgery department since 2010, and hundreds of patients have received good treatment and got rid of the disease.