Diabetic nephropathy has become one of the main groups of hemodialysis population in Europe and America, and the prevalence of diabetic nephropathy is increasing very fast in Beijing, and renal failure caused by diabetic nephropathy has become one of the main causes among hemodialysis patients in our hospital. The clinical prevention and control of diabetic nephropathy by combining Chinese and Western medicine is as follows: (1) Regular review and screening of early renal damage indicators, active application of clinical means combining Chinese and Western medicine to control the content indicators of diabetes such as: (1) control glycated hemoglobin to achieve the standard, control blood glucose to achieve the standard, reduce the fluctuation of blood glucose by more than 30%; (2) active application of ACEI and ARB drugs to control blood pressure to protect the kidney; (3) active (3) actively apply statins to promote lipid standard; (4) regularly review whether uric acid control is up to standard. (2) Active annual screening of diabetic patients for early renal damage indicators such as microproteinuria and interstitial renal damage indicators, for such patients actively use a combination of Chinese and Western medicine clinical treatment, can clearly block the progression to the clinical stage of diabetic nephropathy proteinuria. 3, for diabetic nephropathy clinical stage proteinuria, 24-hour urine protein quantitative analysis greater than 0.5 grams or more, calculated glomerular filtration rate greater than 60ml/min patients, through the combination of Chinese and Western medicine clinical analysis of treatment, has a clear reduction of clinical stage proteinuria role. 4.For patients with diabetic nephropathy clinical phase proteinuria, 24-hour urine protein quantitative analysis greater than 4 grams, calculated glomerular filtration rate less than 60ml/min, through the combination of Chinese and Western medicine clinical analysis treatment efforts to reduce the clinical phase proteinuria, trying to stabilize renal function, reduce cardiovascular and cerebrovascular events as the principle. 5, for diabetic nephropathy clinical phase proteinuria, 24-hour quantitative analysis of urine protein greater than 0.5 grams, calculated glomerular filtration rate less than 30ml/min, the presence of increased blood creatinine, renal function damage patients, through the combination of Chinese and Western medicine clinical analysis of treatment, trying to reduce the clinical phase proteinuria to stabilize renal function, reduce the principle of cardiovascular events at the same time, need to actively analyze the glomerular filtration rate, analysis of volume In addition, we need to analyze the glomerular filtration rate, the magnitude of the increased load, actively control blood pressure, improve cardiac function, anemia, uric acid and many other indicators. For such patients, regardless of whether the blood creatinine reaches the dialysis index or not, if they cannot maintain the body’s water balance, resulting in rapid weight gain, pleural ascites, severe edema or even pericardial effusion, which affects cardiac function, dialysis treatment is recommended; for metabolic acidosis, severe hyperkalemia, normal clinical management, recurring in the short term, difficult to maintain the normal value range, hemodialysis treatment is recommended. 6, diabetic nephropathy combined with Chinese and Western medicine clinical conservative treatment is difficult and requires long-term perseverance, when you have a sharp increase in proteinuria, rapid deterioration of renal function, etc., you must go to the hospital nephrology, and even need a kidney puncture to clarify the pathological changes diagnostic treatment. Diabetic nephropathy patients should especially need to prevent the occurrence of hypoglycemia.