The most important thing to prevent diabetic nephropathy is to effectively control blood glucose and alloglycemic hemoglobin (below 6.5%); appropriately restrict protein intake (generally 0.8-1.0 g/day/kg, below 0.8 g/day/kg after the appearance of proteinuria); actively control blood lipids if combined with hyperlipidemia; actively control blood pressure if combined with hypertension (below 130/80 mmHg), and can recommend the application of ACEI and/or ARB. Improve lifestyle habits, exercise appropriately, control body weight, and smokers should quit smoking. It should be noted that some diabetic patients can have glomerulonephritis at the same time, and the treatment at this time is completely different from diabetic nephropathy. Therefore, diabetic patients with proteinuria should go to a nephrology specialist for early and clear diagnosis and early treatment.