Advances in the treatment of gouty arthritis

  The treatment of gouty arthritis, especially chronic gout, is quite tricky to treat clinically. Sometimes gouty joints flare up frequently when the blood uric acid is normal, and when the infusion is over, gouty attacks follow. Sometimes patients ask why, and there are more times when doctors are at their wits’ end. What is the problem? Actually, the problem of urate precipitation is the key.  The mechanism of urate precipitation is that when uric acid is highly soluble, it forms urate crystals under the action of alkaline substances in the tissues, and under certain conditions, such as local environmental changes, cold, changes in pH, and inflammatory stimuli, uric acid precipitates and causes inflammation of the joint.  Therefore, the key to the treatment of chronic gout is to remove uric acid salts, how to remove uric acid salts, so that the cleanliness of local tissues to normal levels, as if the bathroom sanitary ware to restore the luster, if the local tissues have been corroded by uric acid, the treatment time and tissue repair time will be extended.  Secondly, the problem of liver and kidney function must also be paid attention to in the treatment, pay attention to the preservation of liver and kidney.  If the rheumatology department studies the above problems and summarizes the experience in clinical practice to improve the efficacy, better clinical results will be obtained.