Menopausal depression is a mood disorder that occurs after women enter menopause, characterized by depressed mood, usually appearing in the following groups of states: 1, depressed mood, often feel sad, bitter, anxious, nervous for no reason;, apathy, often feel that life is “meaningless”, many things in life are very cold, even for their hobbies that once interested them. 2. sleep disorders, easy insomnia, early awakening in the early morning, difficult to fall asleep again after waking up, tossing and turning in bed, very distressed and frustrated; 3. poor diet, lack of hunger, do not die eating, eating often as chewing wax; 4. mood changes, especially in the afternoon and at night; 5. accompanied by varying degrees of symptoms of plant nerve dysfunction, such as dizziness, panic. Such as dizziness, panic. Heartbeat, sweating, blood pressure fluctuations, loss of libido, etc. The mechanism of depression in women during menopause is not fully understood, but it may be due to the gradual decrease of estrogen level after menopause, which makes the muscle excitability decrease, coupled with the fact that this period is the “eventful season” of life, which is prone to emotional problems, resulting in a higher incidence of depression than other periods. Data show that the incidence of depression in women during menopause is 15%-20%, so women should be especially alert to depression during menopause. Early detection and treatment. Once the diagnosis of menopausal depression is clear, there is no need to be too nervous and anxious, because depression is not equal to depression, but it can be effectively controlled and completely cured. The key is to cheer up the spirit, eliminate fears and doubts, view the disease correctly and actively cooperate with the doctor’s treatment. In daily life, we should strengthen spiritual and psychological regulation, maintain optimism, and pay attention to arranging the rhythm of life and appropriately participate in some social and sports activities to enhance physical and mental health and promote the relief of depressive symptoms.