Patient: My mother went to the hospital for examination and MRI before New Year’s due to headache and significant memory loss, and was found to have bilateral thalamic tumors 55*42*38mm with grade 1-2 (doctor’s judgment by MRI impact), and received Gamma Knife treatment at the hospital on January 21, 2009. Later on February 10, 2009, he received the second treatment. On February 13, he was discharged from the hospital to recuperate at home, and the effect was obvious after both treatments. However, around February 28, the condition changed (memory loss again, physical weakness, occasional head pain and other symptoms) and recently developed incontinence. During this period, I thought it was the metamorphosis period of the Gamma Knife condition will deteriorate family members did not care. However, after considering the longer period of metamorphosis and contacting the hospital doctor, my mother was told that her recovery was not very satisfactory and that she needed another infusion and was prescribed mannitol, vitamin C, vincristine and other drugs. (My mother has been taking Cordyceps to increase her immune system during her recovery period at home.) My mother’s situation is like the above. Before deciding to do gamma knife, I probably ran through the major hospitals in Shenyang, the results given is that my mother’s lesion location in the thalamus, surgery is difficult to remove the entire tumor, and surgery thalamus in the middle of the skull, surgery is extremely risky, after the Liaoning Provincial Cancer Hospital doctors recommended doing gamma knife. I would like to ask you, do you think Gamma Knife is the best treatment. What should I pay more attention to according to my mother’s situation? Glioma is not completely curable, like my mother’s low-grade but large glioma, after r-knife treatment, is there any possibility for the tumor to disappear, and under normal circumstances, about how long will it recur? Also, I read an article on the internet yesterday, which said that keeping the pH level in the body at a weak alkaline level can inhibit the growth of tumors. Doctor: Glioma is one of the tumors with the worst prognosis among intracranial tumors, and only a very small number of patients can survive for a long time. One characteristic of glioma is that it has a tendency to transform itself to high grade, and there is no method that can inhibit this tendency. The vast majority of gliomas grow in the brain in an infiltrative manner, meaning that there is no clear boundary, and even if the boundary can be distinguished with the naked eye or microscope, it is impossible to be certain that there is no tumor growth outside the boundary. In recent years, there have been no significant clinical advances in the treatment of glioma of very real significance, and the improvement in treatment outcomes has been limited. I understand very well your feelings as a family member, and as a national characteristic of our country, we all do not give up under any circumstances. However, I hope you can understand my “truth” correctly! I say to my patients: when there is a chance of full recovery, we do our best to pursue a full recovery; when there are bound to be sequelae, our goal is to pursue the best quality of life according to our existing conditions; when there is not much time left in life, we have to face it as calmly as possible and live the final countdown in a reasonable way! Your suggestions are: medication to control intracranial pressure; symptomatic treatment, such as medication to control headache; improve diet and nutrition; if your condition still allows, take your mother to do more things she likes; contact relatives and express your affection.