The side effects of growth hormone are as follows: 1. Growth hormone can cause transient hyperglycemia, which usually returns to normal with prolonged use or after discontinuation of the drug. In clinical trials, about 1% of children with short stature had side effects. Local transient reactions (pain, numbness, redness, swelling, etc.) and symptoms of fluid retention (peripheral edema, arthralgia or myalgia) at the injection site are common. 3. Long-term injection of recombinant human growth hormone causes antibody production in a small number of patients, with low antibody binding and no definite clinical significance. However, if the expected growth effect is not achieved, antibodies may be produced and the antibody binding force exceeds 2mg/L, which may affect the efficacy. In other words, growth hormone treatment, side effects are relatively mild, such as redness and swelling at the injection site, rash, etc. (related to the purity of the product) No irreversible side effects have been found in clinical treatment. Growth hormone is relatively safe at therapeutic doses.