Adrenocortical hyperplasia is also known as adrenogenital syndrome or adrenal metaplasia. It is mainly due to defects in the enzymes necessary for the biosynthesis of adrenocortical hormones, resulting in abnormal synthesis of corticosteroids. Clinical manifestations of hypoadrenocorticism vary, such as masculinization in girls and precocious puberty in boys, and hyponatremia or hypertension. Treatment of adrenocortical hyperplasia is still mainly pharmacological, mainly with glucocorticoids and salt corticosteroids. Salt corticosteroids can synergize with glucocorticoids to further reduce ACTH secretion. Oral fludrocortisone can be taken, and after the symptoms improve, the dosage is gradually reduced and discontinued. On the other hand, glucocorticoid treatment can compensate for the deficiency of cortisol secretion by adrenal glands on the one hand, and inhibit the release of excessive ACTH on the other hand, thus reducing the excessive production of androgens, so it can improve the symptoms of masculinization and precocious puberty and ensure the normal growth and development process of the affected children. For example, oral hydrocortisone, prednisone, dexamethasone. In summary, the treatment of adrenocortical hyperplasia in relations is mainly to take salt corticosteroid and glucocorticoid treatment. It is necessary to adjust the drug dose after examination in the hospital and use it under the guidance of the doctor.