Patient Question:Disease:Large head circumference, large motor developmental delay Description:Hello, director. My child is now one and a half years old, the child’s situation is as follows: 1. Sometimes when we take the baby out to play, some neighbors say that the baby’s head is larger, and we have not paid much attention to it. Later on, we found that our baby was a little behind in terms of gross motor movements, which gradually drew our attention. The baby will raise his head around three months, six and a half months will begin to sit, 12 months crawl well, 12 months can also hold the head of the bed or sofa to walk a few steps, now walking independently about 10 meters, but the gait is not stable. 2. The baby started to have fever for two days on August 1st, sneezed on the 4th, and started to cough with phlegm on the 5th. We took him to Tianjin Children’s Hospital, where he was diagnosed with pneumonia and was admitted to the hospital. During his admission, he mentioned his gross motor development to his primary care physician, who then asked him to consult with a brain doctor, who measured his head circumference at 50.5 cm. The doctor gave two suggestions: either to do a head MRI screening + blood and urine genetic metabolic screening or to observe for two to three months. I was not too sure, so I had a head MRI and blood and urine genetic metabolic screening, see the picture for the report. The doctor didn’t tell us what was going on in the child’s head, but only recommended that the blood and urine genetic metabolic screening be repeated in about two months. The report of the child’s blood and urine screening suggested some problems, and the attending doctor said that it might be related to the child’s current infection, and asked us to pay close attention to the child’s growth and development in the future, and to follow up if there are any problems. We would like to ask you, what is the condition of the child’s head? What is the treatment needed? Thank you. I would like to ask you for some advice on the treatment of this condition. Do I need to see a doctor? What preparations should I make before the consultation? The head MRI report shows a slight widening of the extracerebral space and ventricles, but there is no hydrocephalus, no supratentorial obstructive hydrocephalus, and no cranial hypertension, so surgery is not necessary. The results of the genetic and metabolic disease examination are not immediately diagnostic of the child’s disease, and the results may be affected when the child is sick. Zhang Yuqin, the director of the pediatric neurology department of Tianjin Children’s Doctor, is a nationally renowned expert, so you can ask her for a high level consultation. Patient’s question: Hello director, thank you for your reply. I need to ask you the following questions: 1. The child’s extracerebral space and ventricles are slightly widened, can this recover on its own without treatment in the future? Is this a normal condition? Will it affect the child’s intelligence or development? 2. What is the problem of genetic metabolism? What will be the effect of the child’s delayed gross motor development if not intervened? Patient’s question: The child does not have brain dysplasia, right? Doctor: Hello, the slight widening of the extracerebral space and ventricles shown in the head MRI is not serious from the film, and there is a possibility of improvement with the further development of the child’s brain, and no treatment is needed if there is no psychomotor retardation; however, combined with psychomotor retardation or cerebral palsy, drugs that promote neuromyelin development can be used to promote brain development; this imaging change is not directly and necessarily related to the child’s future psychomotor This imaging change is not directly related to the child’s future psychomotor development. It is best to assess psychomotor development once a month for 6 months to detect problems and intervene early. If a child is found to be behind in gross motor development, failure to intervene will definitely affect the child’s motor development, and the child’s clumsy and uncoordinated gait and movement will definitely be bad for him. There are many metabolic diseases such as phenylketonuria and propionic acidemia that have clinical manifestations of neurological damage, such as convulsions and psychomotor developmental backwardness, so the level of medical testing is getting higher and higher, and the more the cause of the disease is found, if the review after 2 months are normal in order to exclude related genetic metabolic diseases, but not all Single The diagnosis of