Usually secondary liver cancer is more serious than primary liver cancer, because primary liver cancer is a malignant tumor occurring in hepatocytes or intrahepatic bile duct cells, most of which are hepatocellular carcinoma; secondary liver cancer often has a history of primary cancer in other parts of the body, mainly colon cancer and other malignant tumors of the digestive tract, and the disease has usually developed to middle or late stage, and the tumor has been metastasized to the liver through different pathways, so the prognosis is poor. 1. Primary liver cancer: by complete resection of the tumor and retaining sufficient volume of functional liver tissue, patients can obtain long-term survival through surgical treatment, and the 5-year survival rate of early stage liver cancer after resection can reach more than 70%. However, the efficacy of resection is related to the function of the liver, the stage of cirrhosis, the location of the tumor, the size and number of the tumor, and whether the envelope is intact or not. 2. Secondary hepatocellular carcinoma: It can be resected by resecting the primary lesion and the secondary lesion of the liver, and the order of resection depends on the actual situation of the patient or the doctor. Its prognosis depends on the nature of the primary cancer, the severity of the primary and secondary cancers at the time of discovery, the efficacy of treatment and other factors, but the overall prognosis is worse than that of primary liver cancer. Patients diagnosed with liver cancer can minimize the adverse effects of the disease through “early detection, early diagnosis and early treatment”, and it is recommended that patients build up their confidence in treatment and take positive actions.